Capabilities

Spatial Solutions 
 
Spatial transcriptomics
In-situ Sequencing
Single Cell solutions
High throughout sequencing
Data to Insights
In depth custom data analysis & integrated multi modal analysis
    • QC data
    • Expression Normalization
    • Segmentation
    • Clustering /Cell typing
    • Custom options
      • Cell–cell distances
      • Cell-cell communication
      • Niche analysis
      • Protein network analysis
 
Spatial Solutions- In Situ Sequencing
 
Vizgen Merscope
  • 1cm2 capture area per run
  • Targeted transcriptional panels- Custom/off the shelf
  • Protein co-detection- up to 6 user selected proteins
  • Fresh frozen, FFPE compatible
 
10x Xenium
  • (2) 12x24mm capture areas per run
  • Targeted transcriptional panels- Custom/off the shelf
  • Up to 5,000 plex RNA detection
  • Compatible with post-processing Protein detection (Akoya, IF, H&E)
  • Fresh frozen, FFPE compatible
 
Spatial Solutions- Spatial Transcriptomics
10x Visium CytAssist
  • 6.5mm2 or 11mm2 capture areas- 2 per slide
      • 55um resolution
      • HD 2um resolution available in 6.5mm2
  • Probe based, whole transcriptome approach for human & mouse
  • Protein co-detection – 35plex including intra & extracellular
  • Compatible with Xenium slides
  • Fresh frozen, FFPE compatible
Curio Seeker
  • 3mm2 or 10mm2 capture areas- 1 per slide
  • 10um resolution
  • Unbiased, whole transcriptome analysis
  • Organism agnostic
  • Fresh frozen compatible only
Curio Trekker
  • 10mm2 capture areas- 1 per slide
  • “True” single cell resolution
  • Compatible with 10x & Fluent
  • Unbiased, single nuclei RNA-seq
  • Organism agnostic
  • Fresh frozen compatible only
 
Single Cell solutions
10x Chromium X
  • Single cell applications for 3’, 5’ & immune profiling, ATAC, multiome, fixed, nuclei
  • Up to 20k cells per sample with GEM-X technologies
  • Compatible with CITE-seq & hashing
  • New methods support on-chip multiplexing and direct blood fixation
 
BioSkryb ResolvOME
  • OMAPiX will be Bioskryb’s FIRST CSP lab
  • One cell per well capture for paired whole genome and polyA RNA single cell analysis
  • Proprietary Primary Template-directed Amplification (PTA) of DNA yields truer
  • representation of genome
  • Higher gene capture means better cell type identification from fewer cells
 
  • CSP for Parse.
  • Combinatorial barcoding method for whole transcriptome and immune profiling
  • Target up to 1M cells in a single assay
  • Proprietary fixation method permeabilizes cell membrane and locks RNA in place for long term storage and stability
 
High Throughput sequencing
 
Element AVITI
    • Rolling cycle amplification yields industry leading
    • quality scores
    • Up to 2x300bp read lengths
    • Compatible with all Illumina libraries
      • No conversion reaction
      • No custom primers
 
Element AVITI24
  • Cytoprofiling with Teton flow cells
  • On flow cell culturing and direct sequencing
  • Simultaneous DNA, RNA, protein and cell morphology analysis
  • Early access/Beta testing for spatial applications
  • Trinity workflow
  • On flow cell target enrichment